Search results for " lead"

showing 10 items of 499 documents

Development, Characterization, and Testing of a SiC-Based Material for Flow Channel Inserts in High-Temperature DCLL Blankets

2018

This work has been carried out within the framework of the EUROfusion Consortium. The views and opinions expressed herein do not necessarily reflect those of the European Commission.

010302 applied physicsNuclear and High Energy PhysicsMaterials scienceFabricationelectrical conductivityBlanketCondensed Matter Physics01 natural sciencesTemperature measurement010305 fluids & plasmasCorrosionchemistry.chemical_compoundThermal conductivitydual-coolant lead-lithium (DCLL) blanketFlexural strengthchemistryCorrosion by PbLi0103 physical sciencesThermalSilicon carbide:NATURAL SCIENCES:Physics [Research Subject Categories]flow channel insert (FCI)thermal conductivityComposite materialporous SiCIEEE Transactions on Plasma Science
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The response of cultured meiofaunal and benthic foraminiferal communities to lead exposure: Results from mesocosm experiments

2018

Lead (Pb) has been regarded as a very toxic element that poses a serious threat to biota. A mesocosm experiment is performed to assess the influence of Pb on meiofaunal (metazoans within 45-500 µm) and benthic foraminiferal (protozoans) communities. To this end, sediments bearing such communities are incubated in mesocosms, exposed to different levels of Pb in seawater, and monitored for up to eight weeks. Concentrations of Pb below 1 ppm in water do not promote a significant increase of this metal in sediments. Relatively high concentrations of Pb seem to affect meiofaunal and benthic foraminiferal communities by reducing their richness or diversity, and the abundance of the most sensitive…

0106 biological sciencesGeologic SedimentsHealth Toxicology and MutagenesisMeiobenthosmeiofauna; foraminifera; lead; mesocosm; sedimentForaminifera010501 environmental sciences01 natural sciencesMesocosmForaminiferaMediterranean SeaEnvironmental ChemistrySeawater0105 earth and related environmental sciencesPollutantDose-Response Relationship Drugbiology010604 marine biology & hydrobiologySedimentBiotaBiodiversityModels Theoreticalbiology.organism_classificationmesocosmsedimentLeadBenthic zoneEnvironmental chemistrymeiofaunaEnvironmental scienceSeawaterWater Pollutants ChemicalEnvironmental MonitoringEnvironmental Toxicology and Chemistry
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Targeting Bacterial Sortase A with Covalent Inhibitors: 27 New Starting Points for Structure-Based Hit-to-Lead Optimization.

2019

Because of its essential role as a bacterial virulence factor, enzyme sortase A (SrtA) has become an attractive target for the development of new antivirulence drugs against Gram-positive infections. Here we describe 27 compounds identified as covalent inhibitors of

0301 basic medicineStaphylococcus aureusMagnetic Resonance SpectroscopyAntivirulenceVirulence Factors030106 microbiologySmall Molecule Libraries03 medical and health sciencesMiceBacterial ProteinsCatalytic DomainDrug DiscoveryAnimalschemistry.chemical_classificationBinding SitesChemistryHit to leadFibroblastsAminoacyltransferasesAnti-Bacterial AgentsMolecular Docking SimulationCysteine Endopeptidases030104 developmental biologyInfectious DiseasesEnzymeBiochemistryCovalent bondSortase ABacterial virulenceNIH 3T3 CellsStructure basedACS infectious diseases
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Exposure to Toxic Heavy Metals Can Influence Homocysteine Metabolism?

2019

Background: Homocysteine is a sulfur amino acid whose metabolism is activated in two pathways: remethylation to methionine, which requires folate and vitamin B12, and transsulfuration to cystathionine, which needs pyridoxal-5’-phosphate. High homocysteine level increases the risk of developing heart disease, stroke, peripheral vascular diseases, and cognitive impairment. Some evidence showed that exposure to these metals increased plasma homocysteine levels. Methods: A systematic review was carried out to clarify the relationship between homocysteine blood levels and exposure to toxic heavy metals (Lead, Cadmium, Mercury, and Chromium). Results: The results of this systematic review i…

0301 basic medicinemedicine.medical_specialtyHyperhomocysteinemiamercury6HomocysteinePhysiologycadmiumvitamin b<sub>6</sub>Clinical BiochemistryCadmium; Chromium; Folate; Lead; Mercury; Methionine; MTHFR; Vitamin B; 12; Vitamin B; 6TranssulfurationReview010501 environmental sciencesfolate01 natural sciencesBiochemistryvitamin B603 medical and health scienceschemistry.chemical_compoundInternal medicinemedicineVitamin B12Vitamin BMolecular Biology0105 earth and related environmental sciencesmethionineleadMethioninebiologybusiness.industrylcsh:RM1-950Cell BiologyMetabolismvitamin B12medicine.diseaseCystathionine beta synthase12lcsh:Therapeutics. Pharmacology030104 developmental biologyEndocrinologychemistryMethylenetetrahydrofolate reductaseMTHFRbiology.proteinchromiumbusinessvitamin b<sub>12</sub>Antioxidants
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Childhood Obesity: The Relationship Between Negative Emotionality, Emotion Regulation, and Parenting Styles

2019

Objectives We aimed to compare obese children and their non-obese counterpart on children’s negative emotionality, emotion regulation and maternal parenting styles and to examine the joint contribution of children’s temperament and maternal styles to children’s obesity. Methods A total of 200 mothers were involved in this study, 100 with children diagnosed with obesity (49 boys, 51 girls; the age ranged from 6 to 12 years), and 100 with children with a normal weight (49 boys, 51 girls; the age ranged from 6 to 12 years). Mothers completed self-report measures on children’s emotionality, emotion regulation, and parenting styles. Results The comparison between the two groups showed that obese…

050103 clinical psychologyAuthoritarian leadership stylemedia_common.quotation_subject05 social sciencesPsychological interventionmedicine.diseaseObesityObesity Temperament Emotional regulation Parenting style ChildhoodChildhood obesityDevelopmental psychologySettore M-PSI/04 - Psicologia Dello Sviluppo E Psicologia Dell'EducazioneEmotionalityDevelopmental and Educational PsychologyParenting stylesmedicine0501 psychology and cognitive sciencesTemperamentPermissiveLife-span and Life-course StudiesPsychology050104 developmental & child psychologymedia_commonJournal of Child and Family Studies
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Governing Complex Strategic Networks: Emergence Versus Enabling Effects

2017

In today’s knowledge-based economy, the sources of competitive advantage increasingly lie in webs of relationships between a variety of firms and organizations that, over time, lead to the emergence of strategic networks. As the performances of both the network actors and the whole network are strictly linked with the coordination and governance of network actors and their activities, this study aims to shed light on the ways in which the processes of network coordination and governance take place. Strategic networks are here viewed as complex adaptive systems, and the twin nature of the processes of strategic network coordination and governance is examined. On one hand, I underscore the em…

050208 financeKnowledge managementbusiness.industryCorporate governancestrategic network complex adaptive system emergence leadership05 social sciencesCompetitive advantageVariety (cybernetics)Lead (geology)0502 economics and businessBusinessComplex adaptive systemSettore SECS-P/08 - Economia E Gestione Delle Imprese050203 business & management
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Leadership and church identity

2018

This article discusses how the theological-spiritual dimension, which has to do with the specific identity of the church, has implications for and partly determines the application of leadership theories and tools in the local church. The article also examines how leadership research can provide the means to realize a church’s theological or spiritual identity or its true nature. This implies a two-directional relationship between theology and leadership. On the one hand, theology should influence how churches are led, and on the other hand, leadership may facilitate the realization of the theological-spiritual dimension.&#x0D; There are a number of important articles on the theology of lea…

060303 religions & theology05 social sciencesIdentity (social science)Local church06 humanities and the arts0603 philosophy ethics and religionlcsh:BV1-5099Focus (linguistics)Epistemologychurch identityEmpirical researchLeadership studiesOrder (exchange)lcsh:Practical Theology0502 economics and businesschurch leadershipLeadership styleleadership and theologySociologyDimension (data warehouse)church development050203 business & managementScandinavian Journal for Leadership and Theology
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3D visualization of engendering collaborative leadership in the space

2012

The paper focuses on collaborative leadership in education and how to illustrate its engendering process in a three-dimensional space. This complex and fluid process is examined as distributed and pedagogical within a Finnish vocational upper secondary educational organization. As a consequence, the notion of distributed pedagogical leadership is used when collaborative leadership in education is studied. Collaborative leadership is argued to consist of the innermost substance of a professional learning community, as attributes of a group of people working together for specific purposes. Therefore, collaborative leadership naturally involves actors, activities, and context. However, the inn…

3D visualizationlcsh:T58.5-58.64Pedagogicallcsh:Information technologySpaceCollaborative LeadershipDistributionProfessional Learning Communitylcsh:P87-96lcsh:Communication. Mass media
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From job demands and resources to work engagement, burnout, life satisfaction, depressive symptoms, and occupational health

2016

This study investigated the cross-lagged associations between work engagement and burnout, and life satisfaction and depressive symptoms, their demands (i.e., workload) and resources (i.e., servant leadership, self-efficacy, resilience) and relationships with occupational health outcomes (i.e., recovery, number of mental health diagnoses, workaholism). This study is a part of an ongoing Occupational Health Study in which 1 415 employees (586 men, 829 women) were followed twice during two years 2011–12 through their occupational health services. The participants filled in a questionnaire on their work engagement, burnout symptoms, well-being, personal and work environmental resources and dem…

515 Psychologymedia_common.quotation_subjecttyön imueducationServant leadership050109 social psychologyBurnoutresurssitOccupational safety and health0502 economics and businessBurnout0501 psychology and cognitive sciencesLIFE SATISFACTIONta512ta515media_commonservant leadershipOccupational healthjob demands and resourcestyöterveysWork engagement05 social sciencesPublic Health Environmental and Occupational HealthLife satisfactionWorkloadMental healthLife SatisfactionPsychiatry and Mental healthjob demandsWork engagementJob demands and resiources8. Economic growthWORK ENGAGEMENTBURNOUTPsychological resiliencePsychologyresourcesServant leadershipSocial psychology050203 business & managementpsychological phenomena and processesClinical psychology
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Transformational leadership development to reduce employee sickness absence: A randomized controlled trial

2022

Objetivo - Dado que muchas organizaciones se enfrentan a un aumento de las bajas por enfermedad entre sus empleados, se ha destacado en la literatura el potencial del liderazgo transformacional para mejorar la salud de los empleados y gestionar más eficazmente las bajas por enfermedad. Sin embargo, las pruebas empíricas existentes sobre esa asociación no son concluyentes y son ambiguas, ya que se basan en métodos de investigación no experimentales y en medidas de resultado subjetivas. Además, sigue sin estar claro si un líder transformacional puede realmente mejorar la salud de los empleados o más bien aumentar la motivación para asistir al trabajo. Además, hay un conocimiento limitado de l…

:CIENCIAS ECONÓMICAS::Organización y dirección de empresas ::Organización de recursos humanos [UNESCO]UNESCO::CIENCIAS ECONÓMICAS::Organización y dirección de empresas ::Organización de recursos humanosTransformational leadershipRandomized controlled trialUNESCO::CIENCIAS MÉDICAS ::Medicina del trabajo::Salud profesional:PSICOLOGÍA::Psicología social ::Liderazgo [UNESCO]:CIENCIAS MÉDICAS ::Medicina del trabajo::Salud profesional [UNESCO]UNESCO::PSICOLOGÍA::Psicología social ::LiderazgoSickness absence
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